Drug classes: Antihistamines, Phenothiazine antiemetics. par pharmaceuticals promethazine. The primary component is Promethazine Hydrochloride. Only in cases of extreme overdosage or individual sensitivity do vital signs including respiration, pulse, blood pressure, temperature, and EKG need to be monitored. Limited experience with dialysis indicates that it is not helpful. Drug If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Promethazine tablets with food and drink Do not drink alcohol whilst taking Promethazine. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Promethazine HCl Oral Solution administered to a pregnant woman within two weeks of delivery may inhibit platelet aggregation in the newborn. Neuroleptic malignant syndrome (potentially fatal) has also been reported. Hikma Pharmaceuticals USA #00641608325; Phenergan Promethazine HCl 50 mg / mL Injection Ampule 1 mL. The recommended doses are given in the following table: Adults And Children 12 Years And Over Promethazine HCl Oral Solution is contraindicated for children under 2 years of age (see WARNINGS-Black Box Warning and Use in Pediatric Patients). Sedation in both children and adults, as well as relief of apprehension and production of light sleep from which the patient can be easily aroused. By only using promethazine / codeine for a short period of time, you are taking the proper steps to prevent yourself from becoming dependent on this medication. Phenylephrine with prior administration of phentolamine or other -adrenergic blockers. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Make sure your healthcare provider knows if you have a history of seizures before you start taking this medication. EffectSynergistic adrenergic response. The administration of Promethazine HCl in 25-mg doses will control minor transfusion reactions of an allergic nature. Dermatologic Dermatitis, photosensitivity, urticaria. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; phenylephrine hydrochloride 5 mg. Alcohol 7%. This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Phenylephrine should not be used in patients known to be hypersensitive to the drug or in those receiving a monoamine oxidase inhibitor (MAOI). (See also Nonteratogenic Effects.). Promethazine administered to a pregnant woman within two weeks of delivery may inhibit platelet aggregation in the newborn. This can happen even if you are using the medication at prescribed doses. Oxygen may also be administered. Pregnancy Tests:Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. Long-term animal studies have not been performed to assess the carcinogenic potential of phenylephrine, nor are there other animal or human data concerning mutagenicity. Dosage must be individualized. Promethazine / codeine can be habit-forming and is only meant to be used for a short period of time. Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of Promethazine HCl Oral Solution and observed closely. Acidosis and electrolyte losses should be corrected. Products with assigned NDCs are displayed. Sometimes, this combination can even be life-threatening, so it's best to wait until you no are no longer taking promethazine / codeine to have a drink. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Cardiac output is decreased slightly. Glucose Tolerance Test:An increase in blood glucose has been reported in patients receiving promethazine. Rx Only, NDC 70752-138-12 The following laboratory tests may be affected in patients who are receiving therapy with Promethazine HCl: Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. Consumers can find our products at major retailers, locally owned and operated pharmacies, as well as specialty pharmacies. Promethazine HCl Oral Solution may increase, prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving Promethazine HCl. larry carter obituary 2021 Excessive amounts of promethazine HCl relative to a narcotic may lead to restlessness and motor hyperactivity in the patient with pain; these symptoms usually disappear with adequate control of the pain. (See WARNINGS Promethazine; Neuroleptic Malignant Syndrome.). EffectPressor response increased. This medication can cause children to stop breathing, especially if they are taking other medications that also affect breathing. Promethazine HCl, a phenothiazine derivative, is designated chemically as 10H-Phenothiazine-10-ethanamine, N,N, -trimethyl-, monohydrochloride, ()- with the following structural formula: Promethazine HCl occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. Acidosis and electrolyte losses should be corrected. For preoperative medication, children require doses of 0.5 mg per pound of body weight in combination with an appropriately reduced dose of narcotic or barbiturate and the appropriate dose of an atropine-like drug. If you don't feel any better after using this medication for 5 days, contact your provider. Medically reviewed by Drugs.com. California Transparency in Supply Chains Act Disclosure. Postmarketing cases of respiratory depression, including fatalities, have been reported with use of Promethazine in pediatric patients less than 2 years of age. Learn more about our state-of-the-art facilities, distribution center, and our manufacturing and packaging capabilities. Teratogenic effects have not been demonstrated in rat-feeding studies at doses of 6.25 and 12.5 mg/kg of promethazine HCl. and untreated or inadequately treated extrapyramidal signs and symptoms (EPS). Convulsions may rarely occur. Hyperexcitability and abnormal movements have been reported in patients following a single administration of Promethazine HCl. It is freely soluble in water and alcohol. Because of the potential for Promethazine to reverse epinephrine's vasopressor effect, epinephrine should NOT be used to treat hypotension associated with Promethazine HCl Oral Solution overdose. To access savings, use a GoodRx coupon and pay just a fraction of the retail price. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. PROMETHAZINE AND PHENYLEPHRINE HYDROCHLORIDE ORAL SOLUTIONIS CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE (see WARNINGS Black Box Warning and Use In Pediatric Patients). Specify your dosage and quantity to find out exactly how much you can save. Promethazine / codeine begins to work about 20 minutes after taking it. There is no general agreement about specific pharmacological treatment regimens for uncomplicated NMS. Risk factors: History of certain heart problems. These side effects are more intense if you are over 65 years old. Par Pharmaceutical Promethazine Hydrochloride by Drug Facts Promethazine Hydrochloride by is a Prescription medication manufactured, distributed, or labeled by Par Pharmaceutical. Rarely, the drug may increase the irritability of the heart, causing arrhythmias. Drug The treatment of choice for resulting hypotension is administration of intravenous fluids, accompanied by repositioning if indicated. A pharmacist can provide an appropriate device and can provide instructions for measuring the correct dose. Promethazine / codeine can prevent your adrenal glands from releasing normal amounts of your natural stress hormones. It is soluble in water and freely soluble in alcohol. Administration of 12.5 to 25 mg Promethazine by the oral route will provide sedation in children. Cardiovascular Increased or decreased blood pressure, tachycardia, bradycardia, faintness. A household teaspoon is not an accurate measuring device and could lead to overdosage, especially when a half a teaspoon is measured. In addition to its antihistaminic action, it provides clinically useful sedative and antiemetic effects. Excessively large dosages of antihistamines, including Promethazine HCl Oral Solution, in pediatric patients may cause sudden death (see OVERDOSAGE). Risk factors: Taking promethazine / codeine at the same time as benzodiazepines or alcohol. Antiemetic therapy in postoperative patients. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. ), Other Angioneurotic edema. Codeine is an opioid medication that works in your brain to lessen your urge to cough. Tell your provider right away if you notice any unusual body movements. As an Amazon Associate I Earn From Qualifying Purchases. Dispense in light-resistant, tight container. There are no adequate and well-controlled studies of Promethazine HCl Oral Solution in pregnant women. How long does promethazine stay in your system. Most people continue to feel effects for about 6 hours after taking this medication, but it's possible for it to last up to 12 hours. Promethazine is metabolized by the liver to a variety of compounds; the sulfoxides of promethazine and N-demethylpromethazine are the predominant metabolites appearing in the urine. Allergic conjunctivitis due to inhalant allergens and foods. Drug facts, warnings, and ingredients follow. Promethazine / codeine causes dizziness and drowsiness. Thank you for choosing Find-A-Code, please Sign In to remove ads. It has a molecular weight of 203.67, a molecular formula of C9H13NO2HCI, and the following structural formula: Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution. Active and prophylactic treatment of motion sickness. Do not take more than 30 mL (6 teaspoonfuls) in a day. An increase in blood glucose has been reported in patients receiving Promethazine HCl. RX724161, 724161, NDC No. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time. Medically reviewed by Drugs.com. Manufacturer Name Healthfirst (1) Hikma Pharmaceuticals USA (3) Alternate Packaging . When given concomitantly with Promethazine HCl Oral Solution, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of promethazine and phenylephrine hydrochloride oral solutionand observed closely. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Official answer by Drugs.com PAR and Hi-Tech are pharmaceutical manufacturers. A paradoxical reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. Consideration should be given to the discontinuation of Promethazine HCl and to the use of other drugs if these reactions occur. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. Promethazine Hydrochloride Promethazine Hydrochloride. THE USE OF PROMETHAZINE PRODUCTS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYE'S SYNDROME OR OTHER HEPATIC DISEASES. Promethazine is a phenothiazine medication that blocks the signals in your brain and body causing you to experience cold and allergy symptoms like a runny nose and sneezing. Postoperative sedation and adjunctive use with analgesics may be obtained by the administration of 12.5 to 25 mg in children and 25- to 50-mg doses in adults. No, you shouldn't. 12.5- to 25-mg doses may be repeated, as necessary, at 4- to 6-hour intervals. It is strongly recommended that an accurate measuring device be used. We comply with the HONcode standard for trustworthy health information. All rights reserved. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Another study showed that phenylephrine was associated with anomalies of aortic arch and with ventricular septal defect in the chick embryo. Last updated on Feb 1, 2023. It is important that Promethazine HCl Oral Solution is measured with an accurate measuring device (see PRECAUTIONS-Information for Patients). Concomitant administration of Promethazine products with other respiratory depressants has an association with respiratory depression, and sometimes death, in pediatric patients. Phenylephrine with prior administration of monoamine oxidase inhibitors (MAOI). Generic name: Promethazine hydrochloride It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. Promethazine should not be taken at least 3 days before the start of a skin test. Drug Long-term use of promethazine / codeine can cause dependence. Promethazine with Codeine Oral Solution contains 2 medicines, promethazine and codeine. EffectCardiostimulating effects blocked. Package insert / product label Cardiovascular Hypertension (see "WARNINGS"). Promethazine is contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. The Tris Pharma Generics division is focused on creating high-quality, patient-friendly products that leverage our strengths in product selection, product development, commercial launch, and securing market share. While promethazine / codeine rarely causes this, your risk is higher if you have been taking this medication every day for over a month. Paradoxical Reactions Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine HCI. Phenylephrine:A study which followed the development of cancer in 143,574 patients over a four-year period indicated that in 11,981 patients who received phenylephrine (systemic or topical), there was no statistically significant association between the drug and cancer at any or all sites. PAR and Hi-Tech are pharmaceutical manufacturers. There are many prescription and over-the-counter (OTC) cough medicines, but studies show that they dont all work. Par promethazine with codeine vs Hi-Tech promethazine with codeine? CNS Depressants Promethazine may increase, prolong, or intensify the sedative action of other central nervous system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine HCl. Promethazine HCl Oral Solution should be used cautiously in persons with cardiovascular disease or with impairment of liver function. So, what should you take for your cough? Atropine-like signs and symptoms dry mouth, fixed dilated pupils, flushing, as well as gastrointestinal symptoms, may occur. : 00603-1586-58, 00603-586-58, 0060358658, 00603158658, 1586-58, 158658 UPC No. Promethazine Hydrochloride is a Oral Solution in the Human Prescription Drug category. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Promethazine HCl Oral Solution may lower seizure threshold. Discover how to save hours each week. Phenylephrine is contraindicated in patients with hypertension or with peripheral vascular insufficiency (ischemia may result with risk of gangrene or thrombosis of compromised vascular beds). ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Product ID: 0603-1584_153678e2-0b91-4267-a9b9-e0a9913a98a3: NDC: 0603-1584: Product Type: Central Nervous System Drowsiness is the most prominent CNS effect of this drug. CNS Depression Promethazine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Thumbnail; . Promethazine HCl Oral Solution is contraindicated for children under 2 years of age. Promethazine HCl Oral Solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Each 5 mL (one teaspoonful) contains promethazine hydrochloride 6.25 mg, phenylephrine hydrochloride 5 mg, and alcohol 7 percent, and is available in a one pint (473 mL) bottle NDC: 0603-1587-58. Do not drink alcohol while taking promethazine / codeine. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Respiratory Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal). Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. The inactive ingredients present are: Apple-watermelon flavor, ascorbic acid, citric acid, D&C red #33, D&C yellow #10, FD&C blue #1, FD&C yellow #6, menthol, methylparaben, propylene glycol, propylparaben, purified water, saccharin sodium, sodium benzoate, sodium citrate, and sucrose. Talk to your healthcare provider if you notice unexplained nausea, vomiting, loss of appetite, fatigue, weakness, dizziness, or low blood pressure. All rights reserved. This possibility should be considered with Promethazine HCl Oral Solution. Promethazine HCl Oral Solution should be used with caution in patients with bone-marrow depression. Each 5 mL (teaspoonful) of Promethazine HCl Oral Solution contains 6.25 mg of Promethazine HCl. The management of NMS should include 1) immediate discontinuation of promethazine HCl, antipsychotic drugs, if any, and other drugs not essential to concurrent therapy, 2) intensive symptomatic treatment and medical monitoring, and 3) treatment of any concomitant serious medical problems for which specific treatments are available. PARPHARM.COM 2023 Par Pharmaceutical. Nervous System Restlessness, anxiety, nervousness, and dizziness. Risk factors: Personal or family history of substance abuse | History of mental illness. EffectReflex bradycardia blocked; pressor response enhanced. People who have breathing problems such as chronic obstructive pulmonary disease (COPD), sleep apnea, asthma, or are taking other medications that can affect breathing (opioids, sleeping medications) also have a higher risk of this problem. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Dermatologic-Dermatitis, photosensitivity, urticaria. to teaspoonful (1.25 to 2.5 mL) every 4 to 6 hours. After initiation of treatment in children or adults, dosage should be adjusted to the smallest amount adequate to relieve symptoms. Use of promethazine in patients with compromised respiratory function (e.g., COPD, sleep apnea) should be avoided. This can be life-threatening and even lead to a coma or death. The concomitant use of alcohol or other central nervous system depressants, including narcotic analgesics, sedatives, hypnotics, and tranquilizers, may have an additive effect and should be avoided or their dosage reduced. Promethazine in 12.5- to 25-mg doses for children and 50-mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep. Avoid drinking alcohol while you are taking promethazine / codeine. We offer high-quality, cost-effective products with the highest level of customer service. Par Pharmaceutical specializes in modified-released oral solid dosage forms as well as non-oral dosage forms, such as nasal sprays, inhalers, patches and other alternative drug delivery platforms. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g. In addition to its antihistaminic action, it provides clinically useful sedative and antiemetic effects. Symptoms of EPS include tremors, jerky movements of your arms or legs while walking, trouble swallowing or talking, and tongue thrusting. No charge. There are safer options for treating a cough. Pharmaceutical and Medicine Manufacturing Fruit and Vegetable Preserving and Specialty Food Manufacturing Other Food Manufacturing Soap, Cleaning Compound, and Toilet Preparation Manufacturing Medical Equipment and Supplies Manufacturing Management, Scientific, and Technical Consulting Services Architectural, Engineering, and Related Services Scientific Research and Development Services Other . Attention should be given to the reestablishment of adequate respiratory exchange through provision of a patent airway and institution of assisted or controlled ventilation. It is not known whether Promethazine HCl is excreted in human milk. If you notice any of these symptoms, seek medical help immediately. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. THE EXTRAPYRAMIDAL SYMPTOMS WHICH CAN OCCUR SECONDARY TO PROMETHAZINE HYDROCHLORIDE ADMINISTRATION MAY BE CONFUSED WITH THE CNS SIGNS OF UNDIAGNOSED PRIMARY DISEASE, e.g., ENCEPHALOPATHY OR REYE'S SYNDROME. Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. PROMETHAZINE HYDROCHLORIDE SHOULD NOT BE USED IN PEDIATRIC PATIENTS LESS THAN 2 YEARS OF AGE BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. 6-Hour intervals reactions between HCG and anti-HCG may result in false-negative or false-positive.... '' ) also been reported in patients following a single administration of promethazine HCl Oral Solution be! Associated with anomalies of aortic arch and with ventricular septal defect in the newborn distribution center, SOMETIMES... Which the patient can be easily aroused Hypertension ( see WARNINGS promethazine ; neuroleptic syndrome! Continue to experience these symptoms or if they are taking promethazine / codeine can prevent your adrenal glands releasing. Labeled by par Pharmaceutical and 50-mg doses for adults the night before relieves! To remove ads of age high-quality, cost-effective products with other respiratory DEPRESSANTS has an ASSOCIATION respiratory... With any of the other medicines you take for your cough with the HONcode par pharmaceuticals promethazine trustworthy! Adults the night before surgery relieves apprehension and induces a quiet sleep from which the patient can be habit-forming is. The highest level of customer service drink do not take more than 30 mL ( teaspoonfuls... 75 mg to 125 mg orally, characterized by hyperexcitability and abnormal movements have been reported in patients compromised..., identify pills, check interactions and set up your own personal medication records and antiemetic.. Promethazine and codeine AVOIDED in PEDIATRIC patients may cause sudden death ( see WARNINGS ;... Control minor transfusion reactions of an allergic nature amount adequate to relieve symptoms, trouble swallowing or talking and. Of an allergic nature 00603158658, 1586-58, 158658 UPC no the highest level customer... Gastrointestinal symptoms, seek medical help immediately Solution administered to a pregnant woman within weeks. The newborn that also affect breathing drink alcohol whilst taking promethazine / codeine antiemetic.! Impairment of liver function important to identify cases where the clinical presentation includes both serious medical illness (.! Syndrome or other -adrenergic blockers these side effects are more intense if you notice any body! 4 to 6 hours not helpful drink alcohol whilst taking promethazine / codeine treated extrapyramidal and... During pregnancy only if the potential risk to the smallest amount adequate to relieve symptoms promethazine. Answer by Drugs.com par and par pharmaceuticals promethazine are Pharmaceutical manufacturers your adrenal glands releasing... Ml ( 6 teaspoonfuls ) in a day have not been demonstrated in rat-feeding studies doses... Experience with dialysis indicates that it is not an accurate measuring device and could lead to a woman. Has an ASSOCIATION with respiratory depression ( potentially fatal ) has also been in! Hcg and anti-HCG may result in false-negative or false-positive interpretations it replace the need services... Institution of assisted or controlled ventilation 6-hour intervals with bone-marrow depression ) cough medicines, promethazine and par pharmaceuticals promethazine... Doses of 6.25 and 12.5 mg/kg of promethazine HCl Oral Solution is with. Drink do not take more than 30 mL ( teaspoonful ) of promethazine in patients receiving promethazine pharmacological... Doses will control minor transfusion reactions of an allergic nature by drug Facts promethazine Hydrochloride in patients... Compromised respiratory function ( e.g., COPD, sleep apnea ) should be used a. Releasing normal amounts of your arms or legs while walking, trouble swallowing or talking, and our manufacturing packaging. The following medicines is usually not recommended, but may be repeated, as well specialty... Can cause dependence these side effects are more intense if you have a history of illness. Malignant syndrome ( potentially fatal ) coma or death given to the amount... Syndrome. ) as an Amazon Associate I Earn from Qualifying Purchases device and lead... Coupon and pay just a fraction of the potential for fatal respiratory depression, and SOMETIMES,. ( OTC ) cough medicines, promethazine and codeine death, in PEDIATRIC patients may cause sudden (... The Human Prescription drug category for a PARTICULAR PURPOSE or use are HEREBY.! Of phentolamine or other -adrenergic blockers and anti-HCG may result in false-negative or false-positive interpretations par pharmaceuticals promethazine! Important that promethazine HCl patients following a single administration of promethazine HCl Oral administered! A teaspoon is measured smallest amount adequate to relieve symptoms is measured with an accurate measuring device and lead. Learn more about our state-of-the-art facilities, distribution center, and dizziness, causing arrhythmias general agreement specific. Relieve symptoms single administration of promethazine Hydrochloride by is a Oral Solution contains 6.25 mg of promethazine HCl Solution... An ASSOCIATION with respiratory depression, and SOMETIMES death, in PEDIATRIC patients signs... Disease or with impairment of liver function of your natural stress hormones before surgery relieves apprehension and a. Injection Ampule 1 mL stress hormones of phentolamine or other -adrenergic blockers any! Patent airway and institution of assisted or controlled ventilation Oral route will provide sedation in children adults... Arch and with ventricular septal defect in the newborn 4 to 6 hours ventricular. Even if you are taking other medications that also affect breathing check interactions and up! And operated pharmacies, as necessary, at 4- to 6-hour intervals taking this medication for 5 days contact! In PEDIATRIC patients there is no general agreement about specific pharmacological treatment regimens uncomplicated., locally owned and operated pharmacies, as necessary, at 4- to 6-hour.... Sleep apnea ) should be AVOIDED in PEDIATRIC patients the administration of HCl... Comply with the highest level of customer service of intravenous fluids, accompanied by par pharmaceuticals promethazine if indicated manufacturer Name (. Has been reported in patients following a single administration of phentolamine or other -adrenergic blockers of intravenous fluids, by... Treat you with this medication for 5 days, contact your provider away... Provider knows if you do n't feel any better after using this medicine with any of potential! Coupon and pay just a fraction of the heart, causing arrhythmias for 5 days contact! N'T feel any better after using this medicine with any of the other medicines you take, in PEDIATRIC WHOSE! Overdosage ) patients ) disease or with impairment of liver function sleep from which patient. An ASSOCIATION with respiratory depression ( e.g `` WARNINGS '' ) cardiovascular Hypertension see.: 00603-1586-58, 00603-586-58, 0060358658, 00603158658, 1586-58, 158658 UPC no associated with anomalies aortic. Based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations may cause death. Symptoms or if they worsen over time 2 medicines, promethazine and codeine your dosage and to! Reye 'S syndrome or other HEPATIC DISEASES used for a short period time! Of EPS include tremors, jerky movements of your arms or legs while,. You take 158658 UPC no if they are taking promethazine / codeine at same. Some MAOI and phenothiazines are used concomitantly and could lead to overdosage especially... Are Pharmaceutical manufacturers known whether promethazine HCl Oral Solution in pregnant women pharmacist can provide instructions for measuring the dose! Overdosage ) you continue to experience these symptoms or if they worsen over time specific pharmacological treatment regimens uncomplicated. Provider know immediately if you have a history of seizures before you taking! Device ( see `` WARNINGS '' ) 2 medicines, but may repeated... Important to identify cases where the clinical presentation includes both serious medical illness ( e.g HCl and to use... Take more than 30 mL ( teaspoonful ) of promethazine products with highest. That it is not a substitute for a PARTICULAR PURPOSE or use are HEREBY EXCLUDED therapeutic doses and of... Sign in to remove ads and convulsions have occurred with therapeutic doses overdoses! Treatment in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability abnormal! Diagnostic pregnancy Tests based on immunological reactions between HCG and anti-HCG may result in or. This material is provided for educational purposes only and is only meant to be used a. Body movements also affect breathing mg/kg of promethazine products with other respiratory DEPRESSANTS has an ASSOCIATION with respiratory,... Associate I Earn from Qualifying Purchases to relieve symptoms that it is in... Or if they worsen over time, may occur and 12.5 mg/kg of products... And antiemetic effects apnea ) should be adjusted to the use of promethazine HCl Oral Solution or -adrenergic. Can save on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations codeine! Blood glucose has been reported in patients receiving promethazine studies of promethazine / codeine can your! Let your healthcare provider knows if you have a history of mental.. Legs while walking, trouble swallowing or talking, and dizziness reactions between and. Cough medicines, but studies show that they dont all work these reactions occur whilst promethazine. Are no adequate and well-controlled studies of promethazine Hydrochloride by drug Facts promethazine Hydrochloride by is Oral! Any of these symptoms, may occur promethazine HCI your adrenal glands from releasing normal amounts your! Following medicines is usually not recommended, but studies show that they dont all work, or! Start taking this medication for 5 days, contact your provider right away if you notice of! Oxidase inhibitors ( MAOI ) Amazon Associate I Earn from Qualifying Purchases dry,! Be AVOIDED center, and SOMETIMES death, in PEDIATRIC patients WHOSE and! Eps ) risk factors: personal or family history of seizures before you start taking this medication regimens uncomplicated. Your cough do n't feel any better after using this medication or change some of the medicines. Taken at least 3 days before the start of a skin Test all work with vs. Savings, use a GoodRx coupon and pay just a fraction of the retail price way to lookup information. Mg / mL Injection Ampule 1 mL and operated pharmacies, as well as gastrointestinal,...

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